If you can tell me your Windows version and if you're using any mods (like PESEdit), I can give you more specific steps.

The most effective way to bypass this error is to use a "No-DVD" or "Fixed EXE" file. This replaces the original game executable with one that does not check for a physical disc. HP PCs - CD/DVD drive is not detected (Windows 10)

If you are a modder (using PES Patch or Smoke Patch), the "No CD" error frequently returns after updating the game. When installing mods, always ensure:

PES 2013 was built for Windows XP and Windows 7. Modern Windows 10/11 security features (like UAC virtualisation and full-screen optimisations) can interfere with legacy drive detection.